Puffo is one of the "lost" languages of the Smurfs in the EMPATH: The Luckiest Smurf story series. It is equivalent to the human language of Italian, following the same language rules of grammar. At the present time of the story series, Puffo is hardly used by any Smurf except for Empath, who has mastered all the lost languages of the Smurfs. Biscotti Smurf, though a descendant of the Puffo clan, hardly knows how to speak in Puffo.
NOTE: Puffo is the actual Italian name for Smurf. It is also Latin for Smurf.