Smurfanilla is a plant that grows in the Smurf Forest in the EMPATH: The Luckiest Smurf story series. It is similar to smurfnip in that it can be used as a smoking herb as well as a medicine, but it gives its users a less powerful high than smurfnip and has no hallucinogenic effects. Lazy and his fellow Smurfs Nabby, Chatty, and Nosey will smoke this on occasion instead of smurfnip. As a medicine, smurfanilla can ease menstrual cramps in Smurfettes and has been used to ease birthing pains. Tapper uses the herb to brew relaxing teas for his customers.

The plant is named after the real-life plant marihuanilla, or Siberian motherwort.